Which Ticks Does Seresto Protect Against?
Posted by Flea Collar Direct on Nov 5th 2026
Seresto repels and kills ticks for 8 months. The labels name four common U.S. tick species, along with the diseases those ticks may transmit.
Dogs: ticks named on the Seresto dog label
| Tick | May transmit |
|---|---|
| Black-legged (deer) tick | Lyme disease, anaplasmosis |
| American dog tick | Rocky Mountain spotted fever, ehrlichiosis |
| Brown dog tick | Ehrlichiosis, anaplasmosis, babesiosis, bartonellosis, canine hemoplasmosis, Rocky Mountain spotted fever |
| Lone Star tick | Ehrlichiosis |
Cats: ticks named on the Seresto Cat label
| Tick | May transmit |
|---|---|
| Deer tick | Lyme disease, anaplasmosis |
| American dog tick | Rocky Mountain spotted fever, cytauxzoonosis, ehrlichiosis |
| Brown dog tick | Ehrlichiosis, anaplasmosis, babesiosis, Rocky Mountain spotted fever |
| Lone Star tick | Cytauxzoonosis, ehrlichiosis |
How Seresto works on ticks
- Repels and kills by contact: ticks don’t have to bite your pet for the collar to work.
- 48 hours: protection against new tick infestations starts 48 hours after fitting.
- 6 hours: after that, new ticks are repelled or killed as quickly as 6 hours.
- Remove attached ticks when you fit the collar; ticks already on your pet may not be killed right away.
Fleas too
Seresto also kills fleas within 24 hours and new fleas within 2 hours, kills flea larvae, and kills fleas before they lay eggs. The dog collar also treats and prevents chewing lice.
Frequently asked questions
Does Seresto kill deer ticks?
Yes. Both the dog and cat labels list black-legged (deer) ticks, which may transmit Lyme disease and anaplasmosis.
Does Seresto prevent Lyme disease?
Seresto repels and kills deer ticks, which may transmit Lyme disease. It does not treat the disease. Ask your veterinarian about Lyme prevention for your pet.
How soon does Seresto work on ticks?
Protection against new ticks starts 48 hours after fitting; new ticks are then repelled or killed as quickly as 6 hours.
Information from the EPA-registered Seresto product labels. This is general product information, not veterinary advice; always read the full label and ask your veterinarian about your pet’s health. Flea Collar Direct is an independent retailer, not affiliated with Elanco. Seresto is a trademark of Elanco or its affiliates.